Clinical Evaluation of Ofloxacin in Symptomatic Lower Urinary Tract Infection

This study was aimed to evaluate the clinical effectiveness and safety of ofloxacin in the treatment of symptomatic lower urinary tract infection in female patients. The study was con­ ducted at Department of Obstetrics and Gynecology, Songklanagarind Hospital, during March 1 to September 30, 1986. We treated 40 female patients, diagnosed as symptomatic lower urinary tract infection by urine culture and antibody-coated bacteria test, with ofloxacin in the dosage of 200 mg. daily for 3 days. All patients returned to follow up 7-14 days after the treatment. The relief of clinical symptoms was shown in 38 out of 40 patients. Bacterial eradication was 31 in 33 pa­ tients. No adverse drug reaction was reported. In our study, ofloxacin has shown to be a useful antibacterial agent in the treatment of symptomatic lower urinary tract infection in terms of high effectiveness, convenience and safety.